Seed-under-leaf is a ball, which also has some flowers. Kumar, K. B. and Kuttan, R. Chemoprotective activity of an extract of Phyllanthus amarus against cyclophosphamide induced toxicity in mice. Indian Journal of Veterinary Medicine 2007;25-28. Mehrotra, R., Rawat, S., Kulshreshtha, D. K., Goyal, P., Patnaik, G. K., and Dhawan, B. N. In vitro effect of Phyllanthus amarus on hepatitis B virus. 1989;14(2):195-201. View abstract. Hamdard Medicus 2006;114-117. Deep in the rain forests of the Amazon grows a small, shrub-like herb called chanca piedra that has powerful healing benefits. Lancet 10-29-1988;2(8618):1017-1018. Chatterjee, M. and Sil, P. C. Hepatoprotective effect of aqueous extract of Phyllanthus niruri on nimesulide-induced oxidative stress in vivo. 2-8-1999;136(1):11-16. Phytochemistry 1995;39(1):217-224. Studies suggest increased water intake reduces the risk of kidney stone formation and recurrences. Germplasm Resources Info. View abstract. Sources of Chanca Piedra & What to Look For, Vitamin C: Uses, Side Effects, Dosage, and Interactions. J Nat Prod 1996;59:196-9. Chanca piedra earned the name stonebreaker for its potential as a cure for kidney stones. Cimanga, R. K., Tona, L., Luyindula, N., Mesia, K., Lusakibanza, M., Musuamba, C. T., Apers, S., De, Bruyne T., Van, Miert S., Hermans, N., Totte, J., Pieters, L., and Vlietinck, A. J. Bhattacharjee, R. and Sil, P. C. Protein isolate from the herb, Phyllanthus niruri L. (Euphorbiaceae), plays hepatoprotective role against carbon tetrachloride induced liver damage via its antioxidant properties. View abstract. 2009;41(2):64-67. A. and Benebo, A. S. Protective effect of the aqueous leaf and seed extract of Phyllanthus amarus on gentamicin and acetaminophen-induced nephrotoxic rats. Bhattacharyya R, Bhattacharya S Wenzel-Mathers M et al. National Institute of Diabetes and Digestive and Kidney Diseases. Tanuja AS, Nivedita Kumar R. Radioprotective effects of Phyllanthus niruri on hematological parameters in Swiss albino mice against gamma radiation. Sign up for our Health Tip of the Day newsletter, and receive daily tips that will help you live your healthiest life. View abstract. Mazumder A, Mahato A Pattnaik AK et al. Although chanca piedra is an herb, it may pose some health risks. Ogunlesi, M Okiei W Osibote E Muotoh C. Antimicrobial activity of the essential oil and the fractional samples obtained from the leaves and seeds of Phyllanthus amarus (Euphorbiaceae). Safety evaluation of aqueous extract of leaves of a plant Phyllanthus amarus, in rat liver. Eur J Pharmacol. When taken with water pills, chanca piedra could cause your blood pressure to be too low.Lithium: Chanca piedra may act as a diuretic (water pill), impacting how efficiently the body gets rid of lithium. When possible, choose a supplement tested by a trusted third party, such as USP, ConsurerLab, or NSF. View abstract. Shokunbi OS, Odetola AA. B. Kumar, K. B. and Kuttan, R. Protective effect of an extract of Phyllanthus amarus against radiation-induced damage in mice.
Newer research also points to the cardioprotective effects of chanca piedra, including reduction of LDL cholesterol and triglycerides. Bruneton J. Pharmacognosy, Phytochemistry, Medicinal Plants. View abstract. Journal of Medicinal and Aromatic Plant Sciences 2003;25(3):743-745. Antiviral Res 1993;20(3):185-192. Pathophysiology. 2011;185(1):323-328. Protocol for callus culture of Phyllanthus amarus Schum and Thonn. Chem Pharm.Bull. The effect of Phyllanthus amarus aqueous extract on blood glucose in non-insulin dependent diabetic patients. Indian Veterinary Journal 2002;79(8):789-793. Study authors said that the chanca piedra might be effective against hepatitis B by slowing the replication (growth) of the hepatitis B virus. Drink lots of water. In Vitro Cellular & Developmental Biology - Plant 2004;40(5):504-508. Indian Drugs 1993;30:338-341. Raphael, K. R., Sabu, M. C., and Kuttan, R. Hypoglycemic effect of methanol extract of Phyllanthus amarus Schum & Thonn on alloxan induced diabetes mellitus in rats and its relation with antioxidant potential. View abstract. Effect of Phyllanthus niruri on metabolic parameters of patients with kidney stone: a perspective for disease prevention. Pill Identifier Tool Quick, Easy, Pill Identification, Drug Interaction Tool Check Potential Drug Interactions, Pharmacy Locator Tool Including 24 Hour, Pharmacies. View abstract. Chandran M, Saverkodiyon S. Molluscicidal activities of plant extract of Phyllanthus niruri on prostate gland of Laevicaulis alte (Ferussac) (Mollusca). View abstract. Ahmeda, A., Hossain, M. A., and Zhari Ismail.
J Ethnopharmacol. Journal of Natural Products 1988;51(1):44-49. Barros ME et al. 2006;89(3):619-623. Acta Pol.Pharm. Bavarva JH, Narasimhacharya VR. Umarani S. Larvicidal action of Phyllanthus niruri against the mosquito Culex quinquefasciatus. No supplement is intended to treat, cure, or prevent disease. As a result, there is little known about any upper dosage limit. In other research, chanca piedra significantly reduced blood sugar levels when people took the herb for 10 days, and studies suggest it may help treat type 2 diabetes. Barros, M. E., Lima, R., Mercuri, L. P., Matos, J. R., Schor, N., and Boim, M. A. View abstract. View abstract. By clicking Accept All Cookies, you agree to the storing of cookies on your device to enhance site navigation, analyze site usage, and assist in our marketing efforts. In vitro study on alpha-amylase inhibitory activity of an Indian medicinal plant, Phyllanthus amarus. Some of these drugs include aspirin, clopidogrel (Plavix), dalteparin (Fragmin), dipyridamole (Persantine), enoxaparin (Lovenox), heparin, ticlopidine (Ticlid), warfarin (Coumadin), and others. The cytotoxic effect and the multidrug resistance reversing action of lignans from Phyllanthus amarus. Using aloe with chana piedra is not recommended. Guha, G., Rajkumar, V., Ashok, Kumar R., and Mathew, L. Aqueous extract of Phyllanthus amarus inhibits chromium(VI)-induced toxicity in MDA-MB-435S cells. Adedapo AA, Abatan MO Idowu SO et al. Kidney Stones: Treatment. Devi, V., Shanbhag, T. V., Bairy, K. L., Rao, N., and Shenoy, S. Effect of Phyllanthus niruri on wound healing in rats. Kannan S, Venkatakrishnan V. Antibacterial activity of Phyllanthus amarus. Redox.Rep. (Taung-ze-phyu) on rabbit model. Adedapo, A. Melzig MF. Sarkar, M. K. and Sil, P. C. Hepatocytes are protected by herb Phyllanthus niruri protein isolate against thioacetamide toxicity. Taking chanca piedra along with other "water pills" might cause the body to lose too much water. Milne A, Hopkirk N, Lucas CR, et al. Adeneye AA, Arogundade MO. J Hepatol. Wang XH, Li CQ Guo XB et al. That is to say, it decreases the body's ability to clot. Phyllanthus Nituri with Referent to Antimicrobial Activity. Viral hepatitis treated with Phyllanthus amarus and milk thistle (Silybum marianum): a case report [corrected]. Nat.Prod.Res 2006;20(4):323-326. Failure of New Zealand hepatitis B carriers to respond to Phyllanthus amarus. In large amounts, chanca piedra may prevent pregnancy, increase your risk of congenital disabilities, or cause low birth weight. Since there is no research on the long-term effects of chanca piedra, it may best to limit your intake of the herbal supplement to 12 weeks or fewer. Moronkola DO, Ogunwande IA Oyewole IO et al. In a 2018 study, 56 people with kidney stones were given 4.5 grams of chanca piedra per day for 12 weeks. Srividya N et al. Niu, J. Chanca piedra contains a chemical that might reduce this effect of norepinephrine. Joshi, B. S., Gawad, D. H., Pelletier, S. W., Kartha, G., and Bhandary, K. Isolation and structure (X-ray analysis) of ent-norsecurinine, an alkaloid from Phyllanthus niruri. Antibacterial effect of Phyllanthus niruri (Chanca Piedra) on three enteropathogens in man. Moshi MJ, Uiso FC Mahunnah RL et al. Pharm Biol. More research in humans is needed to support these claims. You must talk to your healthcare provider about any supplements you plan to take and check in about any potential interactions with other supplements or medications. Investigation on the larvicidal activity of the plant Phyllanthus amarus against Anopheles stephensi. Iizuka, T., Moriyama, H., and Nagai, M. Vasorelaxant effects of methyl brevifolincarboxylate from the leaves of Phyllanthus niruri. Biochemical effect of ethanolic extract of Phyllanthus amarus (Euphorbiaceae) on plasma nitric oxide and penile cyclic guanosine monophosphate (cGMP) in mature male guinea pigs. Biol.Pharm.Bull. View abstract. View abstract. View abstract. View abstract. McHarg T et al. They alsoinspect supplement manufacturers. If youre prone to stones, following a few simple solutions can help: 1. Khanna AK et al. 2012 Jun 13;(6):CD004292. It Could Be Your Adrenals, Tame The Flames: 6 Anti-Inflammatory Supplements, Feeling Sluggish and Low on Energy? Naaz F, Javed A Abdin MZ. One clinical study did note that chanca piedra was stored in a dry space at 59-95 degrees Fahrenheit. Because of this lack of regulation, you must use caution when looking for a safe and effective product. Jeena, K. J., Joy, K. L., and Kuttan, R. Effect of Emblica officinalis, Phyllanthus amarus and Picrorrhiza kurroa on N-nitrosodiethylamine induced hepatocarcinogenesis. Phytother.Res 2001;15(3):265-267. View abstract. Youre Probably Missing One of These Key Nutrients. Ogata, T., Higuchi, H., Mochida, S., Matsumoto, H., Kato, A., Endo, T., Kaji, A., and Kaji, H. HIV-1 reverse transcriptase inhibitor from Phyllanthus niruri. International Journal of Phytomedicine 2011;115-119. Biol.Pharm.Bull. Zeitschrift fr Naturforschung 2006;57-60. View abstract. View abstract. II. Acta Farmaceutica Bonaerense 2004;23:520-523. J Nat.Prod. Shakil, N. A., Pankaj, Kumar, J., Pandey, R. K., and Saxena, D. B. Nematicidal prenylated flavanones from Phyllanthus niruri. Amariin, a di-dehydrohexahydroxydiphenoyl hydrolysable tannin from Phyllanthus amarus. J Ethnopharmacol. Adeneye, A.
Speak with a healthcare professional before taking chanca piedra or any supplement or plant medicine, especially if you are taking any prescription medications. L.Acta Farmaceutica Bonaerense 2003;33:203-207. Journal of Medicinal and Aromatic Plant Sciences 1999;21(1):51. Phytochemistry 2008;69(3):759-764. Thyagarajan, S. P., Thiruneelakantan, K., Subramanian, S., and Sundaravelu, T. In vitro inactivation of HBsAg by Eclipta alba Hassk and Phyllanthus niruri Linn. Journal of Ecotoxicology & Environmental Monitoring 2009;625-628. Taesotikul, T., Dumrongsakulchai, W., Wattanachai, N., Navinpipat, V., Somanabandhu, A., Tassaneeyakul, W., and Tassaneeyakul, W. Inhibitory effects of Phyllanthus amarus and its major lignans on human microsomal cytochrome P450 activities: evidence for CYP3A4 mechanism-based inhibition. 1994;13(1):7-8. Journal of Tropical Medicinal Plants 2004;5(1):5-9. Dietary supplements are not regulated in the United States, meaning the FDA does not approve them for safety and effectiveness before products are marketed. Phenolic constituents in tissue cultures of Phyllanthus niruri. A clinical study about chanca piedra and its effects on kidney stones showed an increase in potassium excretion when taking chanca piedra. Oyewole IO, Moronkola DO Ogunwande IA et al. 2008;46(7):514-520. Inositol hexaphosphate, a carbohydrate found in cereal grains, beans, brown rice and other high-fiber foods helps reduce urinary calcium levels, inhibit crystallization of calcium salts, and lower the risk of stones. Adjene, JO. Molecular Medicine & Advance Sciences 2006;184-189. Using chanca piedra with other herbs that may cause anticoagulation, such as feverfew and ginger, should be avoided. African Journal of Biotechnology 2007;728-731. View abstract. 2000;73(1-2):215-219. Med Pharm Rep. 2019 Apr; 92(2): 153157. This could adversely affect the therapeutic levels of lithium. When oxalate and calcium combine in the stomach, there is a lower incidence of forming oxalate stones. Asian Journal of Experimental Sciences 2010; Bhattacharjee, R. and Sil, P. C. Protein Isolate from the Herb Phyllanthus niruri Modulates Carbon Tetrachloride-Induced Cytotoxicity in Hepatocytes. Vijayanand V, Nagarajan B Vasu K. Efficacy of Azadirachta indica and Phyllanthus amarus in experimental hepatitis in dogs. J Vet.Sci 2003;4(2):181-185. As an herbal medicine, chanca piedra is believed to be effective in treating various conditions of several body systems. Health 2010;511-512. View abstract. Lower the level of salt intake in the diet. The risk of decreased potassium levels in the body exists if too much chanca piedra is taken. Shimizu, M., Horie, S., Terashima, S., Ueno, H., Hayashi, T., Arisawa, M., Suzuki, S., Yoshizaki, M., and Morita, N. Studies on aldose reductase inhibitors from natural products. And senna and aloe contain anthraquinones, compounds that bind calcium and reduce the growth rate of urinary crystals. One health benefit of chanca piedra is that its antioxidants may improve fasting blood sugar levels in certain animals. Planta Med 1991;57(1):98. Antibacterial activity of ethanolic extracts of Phyllanthus amarus against extended spectrum -lactamase producing Escherichia coli isolated from stool samples of HIV sero-positive patients with or without diarrhoea. Hepatoprotection by Phyllanthus amarus and Phyllanthus debilis in CCl4-induced liver dysfunction. Leite, D. F., Kassuya, C. A., Mazzuco, T. L., Silvestre, A., de Melo, L. V., Rehder, V. L., Rumjanek, V. M., and Calixto, J. Sarkar MK, Kinter M Mazumder B et al. In the use of treating specific ailments, the traditional dosage varies. Dhianawaty DD, Padmawinata K Soediro I et al. Dietary protein and potassium, dietdependent net acid load, and risk of incident kidney stones. Ajala, T. O., Igwilo, C. I., Oreagba, I. What should I eat to lower the risk of uric acid stones? Latha, P., Chaitanya, D., and Rukkumani, R. Protective effect of Phyllanthus niruri on alcohol and heated sunflower oil induced hyperlipidemia in Wistar rats. In vitro and in vivo anti-hepatitis B virus activities of the lignan nirtetralin B isolated from Phyllanthus niruri L. J Ethnopharmacol. Clinic study on chronic HBV infection treated by Phyllanthus amarus. Mustofa, Sholikhah, E. N., and Wahyuono, S. In vitro and in vivo antiplasmodial activity and cytotoxicity of extracts of Phyllanthus niruri L. herbs traditionally used to treat malaria in Indonesia. Rajeshkumar, N. V. and Kuttan, R. Phyllanthus amarus extract administration increases the life span of rats with hepatocellular carcinoma. 2003 Nov;92(7):765-8. African Journal of Pharmacy and Pharmacology 2010;402-407. Asian Journal of Biochemistry 2011;291-299. BJU Int. Indian J Exp.Biol. Paris: Lavoisier Publishing, 1995. However, chanca piedra is not approved by the U.S. Food and Drug Administration (FDA) for the treatment of any condition. extract in ethanol treated rats: in vitro and in vivo studies. View abstract. Journal of Natural Products 1987;1156-1157. Ishimaru K, Yoshimatsu K Yamakawa T et al. Pesticide Research Journal 2002;14(1):158-160. Cochrane Database of Systematic Reviews. Jayaram, S. and Thyagarajan, S. P. Inhibition of HBsAg secretion from Alexander cell line by Phyllanthus amarus. Clinical study of hepatoprotective drug Phyllanthus amarus. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using. Purification and characterisation of a novel antioxidant protein molecule from Phyllanthus niruri. View abstract. Than NN, Fotso S Poeggeler B et al. Nutrients. J Pharm Pharmacol. Asian Pacific Journal of Tropical Medicine 2010;105-108. J Urol. View abstract. 7-15-2009;124(2):233-239. Citrate is a chemical that helps prevent kidney stones from developing. Journal of Horticultural Sciences 2008;62-65. Plant Cell, Tissue and Organ Culture 2011;101-110. Teramoto JR, Oliveira RF Santos AS et al. Ali, H., Houghton, P. J., and Soumyanath, A. alpha-Amylase inhibitory activity of some Malaysian plants used to treat diabetes; with particular reference to Phyllanthus amarus. Bioresource Technology: Phenolic compounds, antioxidant activity and in vitro inhibitory potential against key enzymes relevant for hyperglycemia and hypertension of commonly used medicinal plants, herbs, and spices in Latin America., International Brazilian Journal of Urology: Effect of phyllanthus niruri on metabolic parameters of patients with kidney stone: a perspective for disease prevention., International Journal of Current Research in Life Sciences: Phyllantus Niruri: Ethnobotany, Chemistry And Pharmacological Properties Towards Drug Formulations., Journal of Pharmacy and Pharmacology: The pharmacological potential of Phyllanthus niruri., Pharmaceutical Biology: Medicinal plants in the treatment of Helicobacter pylori infections., Phytotherapy Research: Antimicrobial activity of an Amazon medicinal plant (Chancapiedra) (Phyllanthus niruri L.) against Helicobacter pylori and lactic acid bacteria.. Gastroprotective and antioxidant activities of Phyllanthus amarus extracts on absolute ethanol-induced ulcer in albino rats. Adedapo, A. Jayaram S, Thyagarajan SP Sumathi S et al. Chanca piedra may influence blood sugar levels, which most affects people with diabetes. Bhattacharyya R, Bhattacharya S. Development of a potent in vitro source of Phyllanthus amarus roots with pronounced activity against surface antigen of the hepatitis B virus. Linn on burn wound in rats. 1993;40(1):53-58. Tamil, I. G., Dineshkumar, B., Nandhakumar, M., Senthilkumar, M., and Mitra, A. & Thonn. 2014 Nov 28:1-22. 2011 Oct 1;21(19):5901-4. Studies on the possible mechanisms of antidiabetic activity of extract of aerial parts of Phyllanthus niruri. By clicking Subscribe, I agree to the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, COVID Robs Millions of Sense of Smell, Taste, U.S. Nears Top Spot in Global Monkeypox Cases, Diets Heavy in 'Ultra-Processed' Foods Could Harm the Brain, Some CBD Creams, Patches Don't Match Labels, Dr. Whyte's Book: Take Control of Your Diabetes Risk, Artificial Intelligence to Spot the Red Flags ofSuicide Risk, Health News and Information, Delivered to Your Inbox, Becoming a Vegetarian: Foods to Choose From. View abstract. J Ethnopharmacol. J Radiat.Res 2009;50(4):303-309. View abstract. Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings). We've updated our Privacy Policy, which will go in to effect on September 1, 2022. Eliminate refined sugar and high fructose corn syrup. Antihepatotoxic activity of Phyllanthus niruri, Tinospora cordifolia and Ricinus communis. A., Amole, O. O., and Adeneye, A. K. Hypoglycemic and hypocholesterolemic activities of the aqueous leaf and seed extract of Phyllanthus amarus in mice.
Amariinic acid and related ellagitannins from Phyllanthus amarus. Indian Journal of Poultry Science 2007;153-156. Zhu FM, Zhang JQ Zhang XZ et al. Some people use chanca piedra as a liver tonic and for liver problems including hepatitis B. Phytother Res. Bharathi KN, Dattani V. Evaluation of type-I anti-diabetic activity of Phyllanthus niruri and combination of Phyllanthus niruri and Gymnema sylvestre. Chanca piedra may increase the excretion of electrolytes like potassium. Diuretic, hypotensive and hypoglycaemic effect of Phyllanthus amarus. Kiemer, A. K., Hartung, T., Huber, C., and Vollmar, A. M. Phyllanthus amarus has anti-inflammatory potential by inhibition of iNOS, COX-2, and cytokines via the NF-kappaB pathway. Some research shows it reduced kidney stones, reduced bacteria that cause ulcers, and slowed hepatitis B infections. Taking medications that lower blood pressure and chanca piedra may cause your blood pressure to be too low. View abstract. Journal of Ethnopharmacology 2007;503-509. Biomed.Chromatogr. Brook, M. G. Effect of Phyllanthus amarus on chronic carriers of hepatitis B virus. View abstract. Drug Metab Pharmacokinet. Acta Pol.Pharm. When eating oxalate-rich foods, eat or drink those rich in calcium. Chanca piedra is one of the best-studied herbs to prevent kidney stones. Test-tube studies typically involve highly concentrated extracts applied directly to bacterial cells, which isnt how oral chanca piedra supplements would work. Guha, G., Mandal, T., Rajkumar, V., and Ashok, Kumar R. Antimycin A-induced mitochondrial apoptotic cascade is mitigated by phenolic constituents of Phyllanthus amarus aqueous extract in Hep3B cells. Indian J Pharmacol. Lee NYS et al. Cealan A et al. While chanca piedra may reduce blood sugar and blood pressure levels, it should be used with caution if youre already on medication for lowering blood pressure or blood sugar. Immuno-stimulatory and hematopoietic activities of the leaf and seed aqueous extract of Phyllanthus Amarus in normal and cyclophosphamide-treated mice. View abstract. 4. Murugaiyah, V. and Chan, K. L. Determination of four lignans in Phyllanthus niruri L. by a simple high-performance liquid chromatography method with fluorescence detection. Modern studies show it also has powerful benefits in conditions ranging from ulcers to hepatitis B. International Journal of Pharmacognosy 1997;35(3):167-173. View abstract. B., Antarkar, D. S., Deolalikar, R., and Antani, D. H. A two-stage clinical trial of Phyllanthus amarus in hepatitis B carriers: failure to eradicate the surface antigen. Research Journal of Pharmaceutical Biological and Chemical Sciences 2010;335-340. Next to red peppers, you can get the most vitamin C from ________________. Here are some basic guidelines: To prevent oxalate stones, restrict concentrated fruit juices, beets, spinach, rhubarb, tea, dark green vegetables, beer, and chocolate (foods high in oxalates). J Urol. Phytomedicine. Igwe CU, Nwaogu LA Ujuwondu CO. Assessment of the hepatic effects, phytochemical and proximate compositions of Phyllanthus amarus. Warning letter: Herbs America, Inc, Boim MA, Heilberg IP, Schor N. Phyllanthus niruri as a promising alternative treatment for nephrolithiasis. Dawn Sheldon, RN,is a registered nurse and health writer. Srividya N, Periwal S. Diuretic, hypotensive and hypoglycaemic effect of Phyllanthus amarus. Toxicol.Mech.Methods 2010;20(8):498-503. Chanca piedra might decrease blood sugar. Speak with your healthcare provider about taking these supplements if you have a clotting issue or are already taking any of these supplements. High Read our. 2005 - 2019 WebMD LLC. Peace Health. Journal of Pharmacy Research 2009;1869-1872. Boim, M. A., Heilberg, I. P., and Schor, N. Phyllanthus niruri as a promising alternative treatment for nephrolithiasis. Reddy BP, Murthy VN Venkateshwarlu V et al. Effects of oral administration of Phyllanthus amarus leaf extract on the kidneys of adult Wistar rats - a histological study. 2006;43(5):299-305. Beneficial effects of Phyllanthus amarus for chronic hepatitis B, not confirmed. View abstract. HPTLC and HPLC analysis of bioactive phyllanthin from different organs of Phyllanthus amarus. Shanbhag T, Amuthan A Shenoy S et al. Bhattacharjee, R. and Sil, P. C. The protein fraction of Phyllanthus niruri plays a protective role against acetaminophen induced hepatic disorder via its antioxidant properties.
Copyright 2022 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Asian Pac.J Cancer Prev. While the FDA doesn't have the authority to approve dietary supplements for safety and effectiveness or to approve their labels before they're sold to the public, the FDA does evaluate supplement labels for any health claims after they're on the market. Food Chem Toxicol. View abstract. Another study found an extract form, versus tea, effectively blocked the formation of calcium oxalate crystals, the compounds that make up kidney stones. 2004 Nov;154(21-22):523-7. Southeast Asian J Trop.Med Public Health 2007;38(4):609-615. If you are taking prescription medications or other herbal supplements, consult your healthcare provider before taking chanca piedra. Xin-Hua, W., Chang-Qing, L., Xing-Bo, G., and Lin-Chun, F. A comparative study of Phyllanthus amarus compound and interferon in the treatment of chronic viral hepatitis B. Southeast Asian J Trop.Med Public Health 2001;32(1):140-142. Phyllanthus. Our website is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Amaechina, F. C. and Omogbai, E. K. Hypotensive effect of aqueous extract of the leaves of Phyllanthus amarus Schum and Thonn (Euphorbiaceae). 2017 Jul; 9(7): 766. Food Chem Toxicol. 1999;20(4):164-166. Mellinger, C. G., Carbonero, E. R., Noleto, G. R., Cipriani, T. R., Oliveira, M. B., Gorin, P. A., and Iacomini, M. Chemical and biological properties of an arabinogalactan from Phyllanthusniruri.
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